Episode Releases

This episode examines the clinical reality of botanical toxins and the deadly chemistry of poison gardens. From the direct inhibition of the sodium-potassium pump in cardiac myocytes to the quantitative evidence in historic and modern homicides, we explore how the laboratory identifies plant-derived compounds that mimic natural disease.

From Victorian

Israel Keyes was branded an invincible mastermind by the media, sensationalized by true-crime lore, and elevated into a hyper-calculated myth by an eager public. In this episode of The Science of Murder, we dismantle the sanitized boogeyman narrative to conduct a grounded forensic, psychological, and logistical analysis of his

In this episode of The Science of Murder, host Lyssa examines the history, science, and operational realities of criminal profiling, dismantling the Hollywood myth of supernatural mind-reading to expose the probabilistic, data-driven framework of behavioral analysis. The discussion opens by breaking down the contrast between cinematic procedural tropes and

When people think of a murder investigation, the image is cinematic: flashing lights, yellow tape, and detectives pacing a room. But the truth is, a vast number of cases don’t start with a crime scene at all. They start with an anomaly, a paramedic walking into a living room, or

For nearly two decades, Gary Ridgway—the Green River Killer—operated in plain sight along the Pacific Highway corridor, evading a multi-million-dollar task force while maintaining a mundane domestic life and working as a truck painter. In this episode, we break down the forensic and investigative realities behind America’s most prolific convicted

In this episode of The Science of Murder, host Lyssa steps past the sensationalized headlines to take a cold, analytical look at one of the heaviest topics in true crime: filicide, the act of a parent killing their child. Using the Lindsay Clancy proceedings as our initial spark, we

In this episode of The Science of Murder, host Lyssa examines the brutal, unyielding biochemistry of human decay and forensic taphonomy. The discussion opens by dismantling the common true crime myth that concrete slabs or subterranean basements can permanently hide evidence, drawing on the structural and chemical collapse seen

Hollywood loves the clean, neat narrative: a pristine bullet pulled from a wall, laid under a dual-stage comparison microscope next to a test slug, and a definitive match flashed on a monitor. Case closed.

The reality of forensic ballistics is infinitely more complex, spanning the entire life cycle of a

When a toxicologist looks at a poison like cyanide, they see a biological kill switch that silences the room. Organophosphates do the exact opposite—they weld the biological accelerator pedal straight to the floorboards, forcing the body into a violent, hyper-stimulated crisis. In this episode, we step up to the bench